Synthesis and properties of size-expanded DNAs: Toward designed, functional genetic system
Article Abstract:
The description of the design, synthesis and properties of DNA-like molecules in which the base pairs are expanded by benzo homologation is presented where the resultant size-expanded genetic helices are known as xDNA or expanded DNA and yDNA or wide DNA. They are suited for components of new, functioning genetic systems, and fluorescence of expanded DNA bases can also be used in analyzing nucleic acids.
Publication Name: Accounts of Chemical Research
Subject: Science and technology
ISSN: 0001-4842
Year: 2007
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Optical detection of DNA and proteins with cationic polythiophenes
Article Abstract:
The article discusses the technique of fluorescence chain reaction (FCR), a new approach that is used for the optical detection of DNA and proteins with cationic polythiophenes. The described process is found to be very simple and efficient, as it does not employ any chemical manipulations and experimental procedures to obtain the result.
Publication Name: Accounts of Chemical Research
Subject: Science and technology
ISSN: 0001-4842
Year: 2008
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Unlocking the potential of asymmetric hydrogenation at Merck
Article Abstract:
The efforts of Merck scientists toward implementing asymmetric hydrogenation as a core competency within Merck Research Laboratories are presented. Several examples of the development of efficient asymmetric hydrogenation processes are described.
Publication Name: Accounts of Chemical Research
Subject: Science and technology
ISSN: 0001-4842
Year: 2007
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