Mechanisms of mitochondrial disease and the role of exercise: A symposium

Article Abstract:

A symposium was organized to improve the understanding of the mechanisms of mitochondrial disease and the role of exercise to mitochondrial diseases. The variable range of exercise intolerance attributable to the combined effects of impaired mitochondrial oxidative phosphorylation and habitual physical inactivity were presented.

Health aspects, Care and treatment, Risk factors, Exercise

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How is mitochondrial biogenesis affected in mitochondrial disease?

Article Abstract:

A broad range of mitochondrial-specific diseases, termed as mitochondrial myopathies exist in muscles due to mutation in nuclear DNA or mitochondrial DNA. These mutations result in dysfunctional mitochondrial assembly that ultimately leads to reduced ATP production.

Gene mutations, Gene mutation, Genetic aspects, Mitochondrial DNA

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Mitochondrial biogenesis and the role of the protein import pathway

Article Abstract:

The importance of the mitochondrial protein import pathway is discussed. Protein import function in a variety of mitochondrial diseases is examined.

Genetic transcription, Transcription (Genetics), Mitochondria, Protein binding, Origin of life

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