Adaptive evolution of non-coding DNA in Drosophila
Article Abstract:
Several classes of non-coding DNA in Drosophila are evolving slower than synonymous sites, and hence a large fraction of the non-translated genome is functionally important and subject to both purifying selection and adaptive evolution. Studies show that although positive selection is an important facet of protein evolution, adaptive changes to non-coding DNA is considerably more common in the evolution of Drosophila melanogaster.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
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Connectivity of chemosensory neurons is controlled by the gene poxn in Drosophila
Article Abstract:
The pox-neuro (poxn) gene of the fly Drosophila causes touch-sensitive or mechanosensory bristles to turn into chemical-sensitive or chemosensory bristles. Poxn also causes the transformed bristles to form neural connections. This is the first time that the poxn gene has been found to effect the connectivity of neurons, a functioned confirmed by observations of flies with altered neurons.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1992
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A conserved mitotic kinase active at late anaphase-telophase in syncytial Drosophila embryos
Article Abstract:
The Drosophila gene 'polo' can phosphorylate casein in vitro and its kinase activity peaks at late anaphase and telophase. Cyclin B-associated p34(cdc2) kinase, by contrast, peaks on entry into mitosis. The mitotic stage where the polo gene is maximally active is consistent with a hypothesized role in the microtubule organization changes that occur late in anaphase and in telophase.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1993
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