An endogenous cannabinoid (2-AG) is neuroprotective after brain injury
Article Abstract:
Research describing the effects of cannabinoids on brain injuries is presented. In particular the results of administering 2-arachidonoyl glycerol to an injured mouse brain are investigated.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2001
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Anandamide may mediate sleep induction
Article Abstract:
Oleamide, a putative sleep factor, and anandamide, a cannabinoid ligand are reported to cause similar pharmacological effects in mice. Both in vivo and in vitro effects were studied, and the ability of oleamide to affect the K1 anandamide was tested in competition binding experiements. It is possible that some oleamide effects could be mediated by anandamide.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1997
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Trick or treat from food endocannabionoids?
Article Abstract:
It is proposed that the content of endocannabinoids in foods, especially in cocoa, is insufficient to produce cannabis-like effects in mammals. N-acylethanolamines (NAEs) and 2-arachidonoylglycerol (2-AG) were purified from various foods, and quantified by gas chromatography and mass spectrometry. The endocannabinoid, 2-AG was found in relatively high concentrations in milk, and the levels of NAEs ranged between 0.003 and 0.024 mug ml. NAE levels were lower in unfermented cocoa beans than in cocoa powder.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1998
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