CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair
Article Abstract:
The carboxy-terminal region of BRCA2, which interacts directly with the essential recombination protein RAD51, contains a site that is phosphorylated by cyclin-dependent kinanses is reported. The results indicate that S3291 phosphorylation might provide a molecular switch to regulate RAD51 recombination activity, providing new insight into why BRCA2 C-terminal deletions lead to radiation sensitivity and cancer predisposition.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
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Photosystem II core phosphorylation and photosynthetic acclimation require two different protein kinases
Article Abstract:
A second protein kinase, STN8, is required for the quantitative phosphorylation of photosystem II (PSII) core proteins for the plant Arabidopsis. The phosphorylation of light-harvesting (LHCII) proteins, or of an unknown substrate of STN7, is very important for the control of photosynthetic gene expression.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
User Contributions:
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