Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines
Article Abstract:
A demonstration that chromosome nondisjunction is tightly coupled to regulation of cytokinesis in human cell lines, such that nondisjunction results in the formation of tetraploid rather than aneuploid cells, is presented. Results reveal that spontaneously arising binucleated cells exhibited chromosome mis-segregation rates up to 166-fold higher than the overall mitotic population.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
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Ecological interference between fatal diseases
Article Abstract:
A mechanism for ecological interference between pathogens is recently proposed. The historical measles and whooping cough records is analysed and modelled, and it is shown that ecological interference is particularly strong when fatal infections permanently remove susceptibles.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2003
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