Cutaneous lymphocyte antigen is a specialized form of PSGL-1 expressed on skin-homing T cells
Article Abstract:
T cells are pathogenically important in several inflammatory and some malignant skin diseases. Memory T cells infiltrating the skin, have a unique skin-home receptor, cutaneous lymphocyte-associated antigen (CLA). It is reported that CLA is an inducible carbohydrate modified from P-selectin glycoprotein ligand-1. It is proposed that a modification of PSGL-1, mediated by fucosyltransferase VII, acts as a regulatory mechanism for tissue-specific homing of memory T cells.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1997
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Homing in on vertebrates
Article Abstract:
The discovery that rainbow trout develop magnetic sense through learned behaviour is an exciting development in vertebrate research. Other vertebrate organisms are likely to posses the same capabilities. The likely identification of magnetoreceptor cells using sensory nerve traces with confocal laser microscopy are a significant advancement in the field. Further research will verify the properties of the intracellular iron oxide mineral.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1997
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Homing mechanisms in sight
Article Abstract:
Recent research on the homing mechanisms of pigeons may soon shed light on the issue and initiate further studies on pigeon behavior. More data are pouring in which indicate the presence of a magnetic based receptor in some species. More experiments are also being conducted on the mechanism of light-dependent magnetic sensors. The rational behind the 'village effect' or the tendency to fly towards villages is still under debate.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1993
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