Cutting out the middle man
Article Abstract:
A study based on the concept of protein splicing suggests that the function of a desired protein may be controlled by one small molecule. Protein splicing is a self-catalyzing protein modification process in which an internal protein domain, known as the intein, removes itself from the host protein and links itself to the flanking polypeptides, the exteines, to result in the formation of a new polypeptide sequence, thereby regulating the host protein's function in a modified pattern.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006
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Foundations for engineering biology
Article Abstract:
Engineered biological systems are used to manipulate information, construct materials, process chemicals, produce energy, provide food, and help maintain or enhance human health and the environment. Development of foundational technologies based on the ideas of standardization, decoupling and abstraction helps make routine the engineering of synthetic biological systems.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
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