Dynamic organization of motor control within the olivocerebellar system
Article Abstract:
Skilled tongue movement in mice gives rise to regions of the Purkinje cell activity due to input from the olivary neurons. This olivocerbellar control is due to the action of a group of olivary neurons which usually fire when the tongue is fully extended. The action of these neurons is rhythmic, temporally linked to specific movement factors and its pattern can change during the movement events. The timing of the movement is controlled by the firing of the cerebellum's motor neurons through individual muscles that are activated by the simultaneous stimulation of cells by the action of the inferior olive.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1995
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Motor neuron disease model
Article Abstract:
Recent research by M. Sendtner and others asserts that ciliary neurotrophic factor (CNTF) released by implants increases the survival of facial motor neurons of a mouse mutant with progressive motor neuropathy. However, the original description of the mutant found no loss of facial motor neurons even at terminal stages of the neuropathy. But, if the original description of the disease was correct and CNTF protects nerve fibres rather than cells, the results are still of importance even if they are of different theoretical and clinical interest.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1992
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Genetic and epigenetic mechanisms contribute to motor neuron pathfinding
Article Abstract:
Research examining the nonspecific and genetically controlled regulation of motor neuron pathfinding is presented. It was found to be possible to override the genetic programming in certain circumstances.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
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