Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium
Article Abstract:
The bone marrow serves as a reservoir for cardiac precursor cells is suggested by the adult bone marrow (BM) in the process of myocardial replication and regeneration. The reaction of the transformation of the cells from the transgenic mice expressing green fluorescent protein (GFT) to the ischaemic myocardium of wild-type mice is examined.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
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Regulation of oxidation stress by ATM is required for self-renewal haematopoietic stem cells
Article Abstract:
The ATM has an essential function in the reconstitute capacity of haematopoietic stem cells (HSCs) but is not as important for the proliferation or differentiation of progenitors, in a telomere-independent manner. These results show that the self-renewal capacity of HSCs depends on ATM-mediated inhibition of oxidative stress.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
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Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts
Article Abstract:
The trandifferentiation of the haematopoietic stem cells into unexpected phenotypes are suggested. Various clinical trials indicate that haematopoietic stem cells do not readily acquire a cardiac phenotype in myocardial infracts.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
User Contributions:
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