Hypothalamic regulation of sleep and circadian rhythms
Article Abstract:
The brain circuitry and neurotransmitters that regulate the daily cycles of sleep and wakefulness, depends on a network of cell groups that activate the thalamus and the cerebral cortex. A key switch in the hypothalamus shuts off the arousal system during sleep and the other hypothalamic neurons stabilize the switch and their absence results in inappropriate switching of behavioral states, as occurs in narcolepsy.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
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Neural substrates of awakening probed with optogenetic control of hypocretin neurons
Article Abstract:
The impact of the electrical activity of the hypocretin neurons on the changes in the sleeping patterns is explained. The analysis reveals that the photostimulation of these neurons often lead to wakefulness.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
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