Leukaemia/Drosophila homology
Article Abstract:
A human complementary DNA clone, designated AML1 because it marks a subtype of acute myeloid leukemia, is the homologue of runt, one of a group of pair-rule genes that determines morphogenesis in the fly Drosophila melanogaster. The area of homology linking the Drosophila and human polypeptide sequences extends to the conserved exon/intron boundary. Further research is needed to establish AML1's effect on human development.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1992
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The segment polarity network is a robust developmental module
Article Abstract:
Research is presented concerning the segment polarity genes of the fruit fly, Drosophila. Computer simulations are used to demonstrate the modular nature of segment polarity.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
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Polarization of the anterior-posterior axis of C.elegans is a microtubule-directed process
Article Abstract:
Research on polarity cues for Caenorhabditis elegans, and the role of microtubules, is examined in detail.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
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