Mitochondrial membrane remodelling regulated by a conserved rhomboid protease
Article Abstract:
Results demonstrate that intramembrane proteolysis by the intramembrane serine proteases, rhomboid proteins, regulates cellular processes besides signalling. Data indicate that cleavage of the dynamin-like GTPase regulates mitochondrial membrane remodelling in Saccharomyces cerevisiae. The dynamin-like GTPase is one of the two substrates of RBD1 rhomboid protein, which is an inner membrane protein.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2003
User Contributions:
Comment about this article or add new information about this topic:
Feedback control of intercellular signalling in development
Article Abstract:
The fate of cells in animal development depends on precisely-controlled intercellular communication. Research reveals that this form of signalling is regulated to a significant extent by positive and negative feedback loops that give signals information about versatility, precision, and robustness.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
User Contributions:
Comment about this article or add new information about this topic:
Enzyme theory holds water
Article Abstract:
The first high-resolution structure of an intramembrane protease is presented. The rhomboid family is proposed to be serine-type intramembrane proteases and the rhomboid structure gives the first detailed view of intramembrane proteins, correlating with earlier genetic and biomedical studies.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Chiral nematic order in liquid crystals imposed by an engineered inorganic nanostructure. Wide-band reflective polarizers from cholesteric polymer networks with a pitch gradient
- Abstracts: Neuronal position in the developing brain is regulated by mouse disabled-1. Molecular switches in lipid rafts
- Abstracts: Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors. State-dependent cross-inhibition between transmitter-gated cation channels
- Abstracts: Universal nucleic acid-binding domain revealed by crystal structure of the B. subtilis major cold-shock protein
- Abstracts: Effects of habitat on dickcissel abundance and nest success in conservation reserve program fields in Kansas. Factors influencing Mourning Dove nest success in CRP fields