Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
Article Abstract:
Mutations in a newly identified gene which spans more than 500 kilobases and has 12 exons seem to be the cause of the pathogenesis of autosomal recessive juvenile parkinsonism (AR-JP). The protein product of this gene has been named 'Parkin.' There are similarities between Parkin and the ubiquitin family of proteins, which play a role in the pathogenesis of a number of neurodegenerative diseases and are an element of the Lewy bodies in Parkinson's disease. Parkin's defect in AR-JP could hamper the ubiquitin-mediated proteolytic pathway leading to the death of nigral neurons.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1998
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Genome sequence of the ultrasmall unicellular red alga Cyanidioschyzon merolae 10D
Article Abstract:
The information on the essential genes that support the lives of the photosynthetic eukaryotes to higher plants is provided by the compact genomes of ultrasmall unicellular algae. The hot spring algal collection provided by G.Pinto isolate the samples of C. merolae 10D.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
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The medaka draft genome and insights into vertebrtae genome evolution
Article Abstract:
Medaka, a high-quality draft genome sequence of a freshwater teleost is used as a model system for various biology like ecotoxicology, sex determination, and developmental genetics like the vertebrate genome evolution.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
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