Receptor that leaves a sour taste in the mouth
Article Abstract:
Taste receptors located in taste-bud cells are activated leading to the ability to detect taste. A complementary DNA encoding a receptor for sour tastes has been identified. A rat circumvallate papilla cDNA library was constructed to isolate a sour-taste receptor. Clones were expressed in Xenopus laevis oocytes, and RNA transcripts from positive clones resulted in alteration of the extracellular pH to 5.5. Immunohistochemistry was used to determine the subcellular localization of mammalian degenerin-1 protein in the taste buds.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1998
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Stimulation by Rad52 of yeast Rad51-mediated recombination
Article Abstract:
It appears that Rad52 facilitates formation of Rad51 filaments in the presynaptic phase of recombination. Stimulation of the Rad51 reaction and alleviation of the inhibition by Rad52 are both specific to the Rad51 reaction, with this specificity residing in its interaction with Rad51. Binding to Rad51 is necessary for the stimulation of Rad51 reactions by Rad52 protein. This binding prompts the formation of Rad51 nucleoprotein filaments.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1998
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