Repair of demyelinated lesions by transplantation of purified O-2A progenitor cells
Article Abstract:
An investigation was conducted to determine if purified oligodendrocyte precursors could induce remyelination of demyelinated lesions in the central nervous system. Ethidium-bromide-induced lesions were treated with purified O-2A progenitor cells. Three weeks after tranplantation, 90% of demyelinated axons in four out of eight animals showed remyelination. A critical phase of the experiment was the use of cooperating growth factors to amplify the purified populations of O-2A progenitor cells.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1993
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Eggs alone: Human parthenotes: An ethical source of stem cells for therapies?
Article Abstract:
Stem-cell therapy offers hope for diseases that result from a lack of a tissue reservoir of stem cells to replace defective and dying cells, such as heart failure, diabetes, spinal-cord injury, AIDS, and perhaps Alzheimer's disease. The derivation of stem-cell lines from parthenotes depends on the availability of human eggs and on developing the technology to activate them in the laboratory and promote cell division to stem cells.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
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Superior performance of a new affinity purified ANTI-FLAG M2 antibody
Article Abstract:
The ANTI-FLAG M2 monoclonal antibody is useful for the detection, identification, and capture of epitope-tagged fusion proteins by common immunological procedures such as Western blotting, immunoprecipitation, immunocytochemistry and enzyme immunoassay. The new ANTI-FLAG M2 did not bind to proteins lacking the epitope tag, preventing non-specific background FITC generated fluorescence.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
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