The DNA sequence and analysis of human chromosome 13

Article Abstract:

Chromosome 13, the largest acrocentric human chromosome, carries genes involved in cancer and contains the DAOA locus normally associated with bipolar disorder and schizophrenia. The results of the analysis of this chromosome revealed that more than 95.4% of the protein-coding genes have been identified, while 105 putative non-coding genes were found.

Author: Hunt, S.E., Burton, J., Matthews, L.H., Carter, N.P., Clee, C.M., Collins, J.E., Bates, K., Dunham, A., Ashcroft, K.J., Beare, D. M., Burford, D.C., Griffiths-Jones, S., Jones, M.C., Keenan S.J., Oliver, K., Scott, C.E., Ainscough, R, Almeida, J.P., Ambrose, J.P., Andrews, D.T., Ashwell, R. I. S., Babbage, A.K., Bagguley, C.L., Bailey, J., Bannerjee, R., Barlow, K. F., Beasley, H., Bird, C.P., Bray-Allen, S., Ashurst, J.L., Brown, A.J., Brown J. Y., Burill, W., Carder, C., Chapman, J.C., Clamp, M.E., Clark, S.Y., Howe, K.L., Cobley, V., Clarke, G., Clegg, S.C. M., Corby, N., Coville, G. J., Deloukas, P., Dhami, P.

Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004

Biological Product (except Diagnostic) Manufacturing, Drugs, Deoxyribonucleic Acid, DNA

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DNA sequence and analysis of human chromosome 9

Article Abstract:

The human chromosome 9, is highly structurally polymorphic, contains the largest autosomal block heterochromatin, which is heteromorphic in 6-8% humans. The ability to use genomic information to develop new effective therapies will actually benefit from finished human chromosome sequences.

Author: Chen, Y., Hunt, S.E., Burton, J., Plumb, R.W., Carter, N.P., Clee, C.M., Bates, K., Jones, M.C., Oliver, K., Scott, C.E., Almeida, J.P., Babbage, A.K., Bagguley, C.L., Bailey, J., Bird, C.P., Burill, W., Carder, C., Chapman, J.C., Clark, S.Y., Howe, K.L., Clarke, G., Humphray, S.J., Loveland, J.E., Ambrose, K.D., Barlow, K.F., Burford, D., Hunt, A.R., Ainscough, R., Banerjee, R., Barker, D.J., Andrews, T.D., Searle, S., Ashwell, R.I.S., Beasly, H., Beasly, O., Clegg, S., Collier, R.E.

Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004

United States, Structure

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An SNP map of human chromosome 22

Article Abstract:

An evaluation is presented of two large-scale sequencing approaches to identify single nucleotide polymorphisms (SNPs) and a map of 2,730 SNPs on human chromosome 22 is constructed.

Author: Davies, R.M., Chen, Y., Mullikin, J.C., Hunt, S.E., Cole, C.G., Mortimore, B.J., Rice, C.M., Burton, J., Matthews, L.H., Pavitt, R., Plumb, R.W., Sims, S.K., Ainscough, R.M.R., Attwood, J., Bailey, J.M., Barlow, K., Bruskiewich, R.M.M., Butcher, P.N., Carter, N.P., Clee, C.M., Coggill, P.C., Davies, J., Dawson, E., Francis, M.D., Joy, A.A., Lamble, R.G., Langford, C.F., Macarthy, J., Mall, V., Moreland, A., Overton-Larty, E.K., Ross, M.T., Smith, L.C., Steward, C.A., Sulston, J.E., Tinsley, E.J., Turney, K.J., Willey, D.L., Wilson, G.D., McMurray, A.A., Dunham, I., Rogers, J., Bentley, D.R.

Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000

Nucleotide sequence, Base sequence, Chromosome mapping, Genetic polymorphisms

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Subjects list: Research, Human chromosomes

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Abstracts

Zoology and wildlife conservation

The DNA sequence and analysis of human chromosome 13

DNA sequence and analysis of human chromosome 9

An SNP map of human chromosome 22