Variable cell number in nematodes
Article Abstract:
It has been established that many, possibly most, nematode species are not eutelic in the epidermis. In this way, they are similar to other model organisms such as fruitflies and mice. This research involved determining the among-individual variance (Vi) of epidermal nuclear number in adults of 13 species of free-living nematode from three families. It was found that Vi rises with the probability of deviating from the species' canonical lineage. For a given probability of lineage variation, more complex lineages produce a higher Vi than simpler lineages.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1999
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Simple worms, complex genes
Article Abstract:
The mab-5 gene, a Caenorhabditis elegans homologue of the Drosophila Antennapedia Hox gene, is regulated several times during postembryonic development. Embryonic expression of mab-5 in posterior body cells is mediated by lineal mechanism. Mutations in mab-5 and Hox cluster influence only minor aspects of cell differentiation that affect heterotypic cellular association specificity. These findings contradict the traditional view that Hox genes are regulated early during development and continue as markers to specify regional identity.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1996
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Specification of sense-organ identity by a Caenorhabditis elegans Pax-6 homologue
Article Abstract:
The Pax-6 genes in the nematode, Caenorhabditis elegans are involved in the development of many organs. The mab-18 form of the Pax-6 gene is required for the control of the release of the proteins necessary for cell recognition and assemblage of the sense-organs, while the vab-3 form is required in the coding of the epidermal blast cells. The Pax-6 transcription factor consists of a paired region and a paired-type homeodomain.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1995
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