Zinc transporter LIVI controls epithelial-mesenchymal transition in zebrafish gastrula organizer
Article Abstract:
An identification of LIV1, abreast-cancer -associated zinc transporter protein, as a downstream target of STAT3 that is essential and sufficient for STAT3's cell-autonomous role in the epithelial-mesenchymal transition (EMT) of zebrafish gastrula organizer cells is presented. The essentiality of the LIV1 for the nuclear localization of zinc-finger protein Snail, a master regulator of EMT is demonstrated.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
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Time for a medical
Article Abstract:
The resignation of Pfizer's chief financial officer and concerns on the safety of GlaxoSmithKline's diabetes drug Avandia have created great tension for the pharmaceutical industry in the U.S. This has come at an unfortunate time when the industry is still coming to terms with the problems with regulation and business.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
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Keeping faith with trial volunteers
Article Abstract:
The equal partnership between the funding pharmaceutical company academic investigators in clinical trials ensure that interests of patients participating in the trials are not compromised.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
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