A dedicated Wnt secretion factor
Article Abstract:
A new Wnt pathway component called wntless or evenness interrupted is identified. This gene encodes a new multipass transmembrane protein that is conserved in metazoans from worms to humans and two alleles of wis/evi are observed in a genetic screen for recessive suppressors of a Wnt gain-of-function phenotype in the Drosophila eye.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
Secretion of Wnt ligands requires Evi, a conserved transmembrane protein
Article Abstract:
A conserved multipass transmembrane protein, Evenness interrupted (Evi/Wls) is identified through an RNAi survey for transmembrane proteins involved in Drosophila Wingless (Wg) signaling. Wg is retained by evi mutant cells which may be the founding member of a gene family specifically required for Wg/Wnt secretion.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila
Article Abstract:
A predicated transmembrane protein, Eater, which is involved in phagocytosis in Drosophila, was identified. Results suggested that Eater was a major phagocytic receptor for a range of bacterial pathogens in Drosophila and provided a powerful model to address the role of phagocytosis in vivo.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2005
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: The T-box transcription factor Tbx18 maintains the separation of anterior and posterior somite compartments. The prepattern transcription factor Irx3 directs nephron segment identity
- Abstracts: Necrotic death as a cell fate. Growth factor regulation of autophagy and cell survival in the absence of apoptosis
- Abstracts: Identification of a multicomponent complex required for outer membrane biogenesis in Escherichia coli. Chemical conditionality: A genetic strategy to probe organelle assembly
- Abstracts: A yeast platform for the production of single-chain antibody-green fluorescent protein fusions. Seasonal change in bacterial flora and biomass in mountain snow from the Tateyama Mountains, Japan, analyzed by 165 rRNA gene sequencing and real-time PCR
- Abstracts: Cotranscriptional Set2 methylation of histone H3 kysine 36 recruits a repressive Rpd3 complex. Navigating the chaperone network: An integrative mediated by the Hsp90 chaperone