The T-box transcription factor Tbx18 maintains the separation of anterior and posterior somite compartments

Article Abstract:

A study demonstrating that maintenance of anterior-posterior (AP)-somite polarity is mediated by the T-box transcription factor Tbx18 is presented. Findings show that specification and maintenance of anterior and posterior somite halves are separate processes with distinct molecular requirements and that the T-box transcription factor Tbx18 maintains the integrity of the anterior somite compartment.

Somite, Somites (Embryology)

---

TBX22 missense mutations found in patients with X-linked cleft palate affect DNA binding, sumoylation and transcriptional repression

Article Abstract:

A study of the 10 different naturally occurring missense mutations that are phenotypically equivalent to loss-of-function alleles was done by investigating the preferred recognition sequence for T-box transcription factor TBX22. The TBX22 functions as a transcriptional repressor and that TBX22 missense mutations results in impaired repression activity.

United States, Gene mutations, Gene mutation, DNA-ligand interactions, DNA binding

---

The prepattern transcription factor Irx3 directs nephron segment identity

Article Abstract:

The paper studies the prepattern transcription factor Irx3, a member of the Iroquois gene family that identifies nephron segment.

Genetic aspects, Xenopus, Structure, Kidney tubules, Organogenesis, Report, Nephrons

Similar abstracts:

• Abstracts: The transcriptional factor Net regulates the angiogenic switch. Enhancer-promoter communication mediated by Chip during Pannier-driven proneural patterning is regulated by Osa
• Abstracts: Transcriptional oscillation of Lunatic fringe is essential for somitogenesis. The mouse homeobox gene Not is required for caudal notochord development and affected by the truncate mutation
• Abstracts: Senseless, a Zn finger transcription factor, is necessary and sufficient for sensory organ development in Drosophila
• Abstracts: Smad transcription factors. Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction
• Abstracts: Conserved MYC transcription factors play a key role in jasmonate signaling both in tomato and Arabidopsis. Environmental regulation operating at the promoter clearance step of bacterial transcription

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.