A mutant of Listeria monocytogenes L028 unable to induce an acid tolerance response displays diminished virulence in a murine model

Article Abstract:

A research was conducted to study the ability of a Listeria monocytogenes L028 mutant to induce an acid tolerance response (ATR) using log-phase cultures centrifuged in TSB-YE preheated to either 42 degrees C or 37 degrees C. The acid-adapted L028 was showed to exhibit cross-protection against other stresses while the ATR1 cells which reached the spleens had a growth rate similar to that of the parent cells. Moreover, the mutant showed a capability to adapt to acid stress which is important for the pathogenesis of L. monocytogenes.

Analysis, Testing, Virulence (Microbiology), Listeria monocytogenes

---

Construction of p16Slux, a novel vector for improved bioluminescent labeling of gram-negative bacteria

Article Abstract:

A novel vector is constructed for the constitutive luminescent tagging of gram-negative bacteria by using site-specific integration into the 16S locus of the bacterial chromosome. Many gram-negative pathogens are successfully tagged by using this vector and this system is validated during murine infections of living animals.

Science & research, Research, Genetic aspects, Gram-negative bacteria, Bacterial infections, Mutagenesis, Luminescence

---

Similar abstracts:

• Abstracts: Tolerance of Listeria monocytogenes to cell envelope-acting antimicrobial agents is Dependent on SigB. Presence of GadD1 glutamate decarboxylase in selected Listeria monocytogenes strains is associated with an ability to grow at low pH
• Abstracts: Bias in the Listeria monocytogens enrichment procedure: Lineage 2 strains outcompete lineage 1 strains in University of Vermont selective enrichments
• Abstracts: Shiga toxin 2e-producing Escherichia coli isolates from humans and pigs differ in their virulence profiles and interactions with intestinal epithelial cells
• Abstracts: Reliable and rapid identification of Listeria monocytogenes and Listeria species by artificial neural network-based Fourier transform infrared spectroscopy
• Abstracts: Quantitative trait loci for thermotolerance phenotypes in Drosophila melanogaster. Progress and prospects in mapping recent selection in the genome

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.