A novel all helix fold of the AP180 amino-terminal domain for phosphoinositide binding and clathrin assembly in synaptic vesicle endocytosis
Article Abstract:
Research has been conducted on the clathrin-mediated endocytosis. The role of this endocytosis in retrieving synaptic vehicles from the plasma membrane following exocytosis has been investigated and the results are presented.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2001
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Crystal structure of Pl-Scel, a homing endonuclease with protein splicing activity
Article Abstract:
The crystal structure of the the yeast PI-Scel bifunctional protein was analyzed at 2.4 angstrom resolution to characterize the structure-function relationships of the protein. Analysis of the crystal structure of the yeast PI-Scel indicated the presence of a highly conserved amino acid residue in the nucleolytic active site. The bifunctional yeast protein also exhibited structural-functional duality and acted as a monomeric endonuclease.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1997
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