Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network
Article Abstract:
The expressions of 49 mouse nuclear receptor (NR) mRNAs in 39 tissues were surveyed to establish the anatomical expression profiles. The data reveal a hierarchical transcriptional circuitry that extends beyond individual tissues to form a meganetwork governing physiology on an organismal scale.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
Crystal structure of the lambda repressor C-terminal domain provides a model for cooperative operator binding
Article Abstract:
Research has been conducted on the transcription factor interactions. The x-ray crystal structure of the lambda repressor C-terminal domain determined via multiwavelength anomalous diffraction is described.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2000
User Contributions:
Comment about this article or add new information about this topic:
The RNA binding protein Pub 1 modulates the stability of transcripts containing upstream open reading frames
Article Abstract:
Research has been conducted on the nonsense-mediated mRNA decay (NMD) pathway. Prevention of the rapid NMD by a stabilizer element via interaction with the RNA binding protein Pub 1 has been investigated.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2000
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Combinatorial roles of the nuclear receptor corepressor in transcription and development. Identification of a regulated pathway for nuclear pre-mRNA turnover
- Abstracts: Structural basis of DNA recognition by the heterodimeric cell cycle transcription factore E2F-DP. Transient depletion of xDnmt1 leads to premature gene activation in Xenopus embryos
- Abstracts: Chromate-reducing properties of soluble flavoproteins from Pseudomonas putida and Escherichia coli. Purification to homogeneity and characterization of a novel Pseudomonas putida chromate reductase
- Abstracts: A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Calcineurin signaling and muscle remodeling