Antagonistic activity of Lactobacillus acidophilus LB against intracellular Salmonella enterica serovar typhimurium infecting human enterocyte-like Caco-2/TC-7 cells
Article Abstract:
Lactobacillus acidophilus LB inhibits Salmonella enterica serovar Typhimurium by decreasing the number of apical serovar Typhimurium F-actin rearrangements in infected cells, inhibiting intracellular growth of serovar Typhimurium, and inhibiting serovar Typhimurium-induced interleukin-8 production. This was the conclusion of researchers who studied the interaction of the two bacteria in an enterocyte cell line.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 2000
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The human Lactobacillus acidophilus strain LA1 secretes a nonbacteriocin antibacterial substance(s) active in vitro and in vivo
Article Abstract:
The human Lactobacilus acidophilus strain LA1 was studied to examine its inhibitory activity against the process of pathogenicity of enterovirulent bacteria is due to the production of secreted antimicrobial substances. The study demonstrated a strain of LA1 developed its antibacterial activity in conventional mouse models orally infected by Salmonella typhimurium. Results show that he human L. acidophilus LA1 produces antibacterial activity that is effective in vitro against gram-positive and gram negative pathogens.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 1997
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Antagonistic activity against Helicobacter infection in vitro and in vivo by the human Lactobacillus acidophilus strain LB
Article Abstract:
The antagonistic behavior of the human Lactobacillus acidophilus strain LB against Helicobacter pylori in vitro and in vivo was investigated. The LB strain was obserbed to secrete an antimicrobial substance other than lactic acid which is not affected by heat and only slightly sensitive to enzymatic treatment. Findings showed that the spent culture supernatant of strain LB radically reduces the viability of H. pylori, protects mice against H. felis infection, and prevents H. pylori and H. felis urease activity in vitro and in vivo, respectively.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 1998
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