Atonal is a proneural gene that directs chordotonal organ formation in the Drosophila peripheral nervous system
Article Abstract:
The isolation of a gene, atonal (ato), proves that it is a proneural gene needed for the development of chordotonal organs, contradicting previous indications that only the development of the precursor of external sense organs needs the proneural genes of the achaete-scute complex (ASC) in the Drosophila peripheral nervous system. The ectopic expression of the ASC genes enhances the development of external sense organs, and selectively enhances the development of chordotonal organs, proving that neuronal identity is significantly influenced by proneural genes.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1993
User Contributions:
Comment about this article or add new information about this topic:
Partner of numb colocalizes with numb during mitosis and directs numb asymmetric localization in Drosophila neural and muscle progenitors
Article Abstract:
The cell membrane-associated protein Numb is asymmetrically distributed between two daughter cells conferring distinct daughter cell fates during mitosis of multiple types of precursor cells in Drosophila.Partner of Numb (PON) has been identified as a novel gene product which is asymmetrically localized during mitosis and colocalizes with Numb. Numb localization in muscle progenitors is disrupted by loss of pon function. PON responds to polarity cues in neural precursors and epithelial cells.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1998
User Contributions:
Comment about this article or add new information about this topic:
Spatially localized rhomboid is required for establishment of the dorsal-ventral axis in Drosophila oogenesis
Article Abstract:
A group of genes acting maternally is required to establish the dorsal-ventral asymmetry of the Drosophila embryo. Rhomboid encodes a protein that is situated on the apical surface of the dorsal-anterior follicle cells encircling the oocyte. Any lapse in the rho function results in the ventralization of the eggshell and the embryo, but ectopic expression leads to dorsalization of both structures. Spatially restricted rho is imperative for the formation of the dorsal-ventral axis.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1993
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Structural and functional organization of the Yersinia pestis bacteriocin pesticin gene cluster. The gene cluster directing O-antigen biosynthesis in Yersinia enterocolitica serotype O:8:identification of the genes for mannose and galactose biosynthesis and the gene for the O-antigen polymerase
- Abstracts: Coordination of growth and cell division in the Drosophila wing. Endoreplication cell cycles: more for less
- Abstracts: Conjugational recombination in Escherichia coli: genetic analysis of recombinant formation in Hfr X F- crosses
- Abstracts: The fertility effects of pericentric inversions in Drosophila melanogaster. A cytogenetic and genetic characterization of a group of closely linked second chromosome mutations that suppress position-effect variegation in Drosophila melanogaster
- Abstracts: Analysis of mitochondrial DNA indicates that domestic sheep are derived from two different ancestral maternal sources: No evidence for contributions from Urial and Argali sheep