Control of cell lineage-specific development and transcription by bHLH-PAS proteins

Article Abstract:

Progress has been made in what is known about the nature of the basic-helix-loop-helix-PAS (bHLH-PAS) protein subfamily. Ways by which bHLH-PAS proteins regulate lineage-specific gene transcription have been studied. They affect development of the Drosophila CNS midline cells and respiratory system. The bHLH-PAS/Arnt regulatory cassette has implications that relate to evolution. Regulation of cell lineage-specific development has been investigated as has transcription by bHLH-PAS proteins. Underlying mechanisms may exist in invertebrates and vertebrates.

Central nervous system, Proteins, Genetic transcription, Transcription (Genetics), Cell lines

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Spineless provides a little backbone for dendritic morphogenesis

Article Abstract:

The role of the Spineless (Ss) basic helix-loop-helix-PAS (bHLH-PAS) transcription factor in controlling dendrite morphogenesis is described as well as the contributions of other regulatory proteins is reviewed. It is concluded that Ss employs a variety of biochemical mechanisms to control a multiplicity of developmental and physiological processes.

Science & research, Report

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Genes regulating dendritic outgrowth, branching, and routing in Drosophila

Article Abstract:

The article explores molecular mechanisms controlling dendrite morphogenesis in the embryonic peripheral nervous system of Drosophila. Genes responsible for the dendrite development are described.

United States, Physiological aspects, Gene mutations, Gene mutation, Molecular biology, Neurons

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