DNA deamination mediates innate immunity to retroviral infection
Article Abstract:
Research indicates that built-in immunity to retroviruses results from DNA deamination as shown by the incorporation of DNA deaminase into virions during viral development triggering viral destruction. Data show that the enzyme is involved in a massive deamination of deoxycytidine to deoxyuridine within the retroviral cDNA strand.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2003
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Extracellular crosstalk: when GDNF meets N-CAM
Article Abstract:
The authors discuss the study on a receptor for glial cell line-derived neurotrophic factor. The topics of interest include RET-dependent glial cell line-derived neurotrophic factor signaling and the role of glial cell line-derived neurotrophic factor-neural cell adhesion molecule pathway.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2003
User Contributions:
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