Delta and Serrate are redundant Notch ligands required for asymmetric cell divisions within the Drosophila sensory organ lineage

Article Abstract:

Asymmetric divisions make it possible for a precursor to produce four different cells of a sensory organ lineage (SOL) of a Drosophila. The process must have cell-cell communication via the Notch (N) receptor. Mitotic recombination that takes away the N ligand Delta (D1) or Serrate (Ser) in the SOL does not have a large effect, if any. Removal of both D1 and Ser causes changes in the fate of the cell similar to those associated with the N phenotype. D1 and Ser do the same things in helping signaling between daughter cells to determine differing cell fates.

Genetic regulation, Cell differentiation, Cell division

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Drosophila ribosomal proteins are associated with linker histone H1 and suppress gene transcription

Article Abstract:

Study is conducted to demonstrate that specific components of Drosophila melanogaster ribosomes copurify with linker histone H1, and this association of nuclear ribosomal proteins with histone H1 is specific, and the colocalization occurs on condensed chromatin in vivo. This study provides evidence for a previously undefined link between ribosomal proteins and chromatin, and suggests a role for this association in transcriptional regulation in higher enkaryotes.

China, Histones, Genetic transcription, Transcription (Genetics), Ribosomal proteins, Structure

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Conversion of neurons and glia to external-cell fates in the external sensory organs of Drosophila hamlet mutants by a cousin-cousin cell-type respecification

Article Abstract:

Analysis of HAMLET(HAM) function in Drosophila external sensory organ(ESO) lineage elaboration is given. The study provides an useful insight into occurrence of cell lineage via cousin-cousin cell-fate respecification event.

Gene mutations, Gene mutation, Genetic research

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