ISG15 modification of the eIF4E cognate 4EHP enhances cap structure-binding activity of 4EHP
Article Abstract:
Various properties, including the interferon, genotoxic stress and pathogen infection are highly responsible for activating the protein modification by ISG15 (ISGylation), the ubiquitin-like molecule that plays a very important role in the innate immune responses. The analysis states that the ISGylation of 4EHP, an mRNA cap structure-binding protein, is very essential and highly affects the cap-structure dependent translation control in several immune responses.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2007
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TAp63? induces AP-2? as an early event in epidermal morphogenesis
Article Abstract:
The role of the transcription factor TAp63? in promoting expression of AP-2? gene which leads to the development of epidermis in vertebrate embryos is studied.
Publication Name: Developmental Biology
Subject: Biological sciences
ISSN: 0012-1606
Year: 2006
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