Effects of low-shear modeled microgravity on cell function, gene expression and phenotype in Saccharomyces cerevisiae
Article Abstract:
The behavior of Saccharomyces cerevisiae grown in a high-aspect-ratio vessel, which stimulates the low-shear and microgravity conditions encountered in spaceflight was examined. It was hypothesized that altered gene expression in cells grown in low-shear modeled microgravity might result in changes in the yeast phenotypic and functional characteristics that could be identified and measured by conventional microscopic and fluorescent staining techniques.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 2006
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Multiple contributions of peroxisomal metabolic function to fungal pathogenicity in Colletotrichum lagenarium
Article Abstract:
Saccharomyces cerevisiae isocitrate lyase (ICL1) of Colletotricluan lagenarium, which encodes isocitrate lyase involved in the glyoxylate cycle in peroxisornes is isolated and functionally characterized to verify the roles of peroxisome-associated metabolism in fungal pathogenicity. Peroxisomal metabolic pathways play functional roles in appressorial melanization and subsequent host invasion steps that requires the glyoxylate cycle.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 2006
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