L-Valine production with pyruvate dehydrogenase complex-deficient Corynebacterium glutamicum
Article Abstract:
The effect of pyruvate dehydrogenase complex (PDHC) inactivation in Corynebacterium glutamicum on the formation of organic acids and amino acids is investigated. The results have shown that the PDHC-deficient mutant of Corynebacterium glutamicum wild type (WT) have produced pyruvate, L-valine, L-alanine, thus directing the carbon flux from glucose to L-valine by overexpression of L-valine biosynthetic genes.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 2007
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Sequence analysis of the 144-kilobase accessory plasmid pSmeSM11a, isolated from a dominant Sinorhizobium meliloti strain identified during a long-term field release experiment
Article Abstract:
The complete nucleotide sequence of an accessory plasmid (pSmeSM11a) is described that is isolated from a dominant indigenous Sinorhizobium meliloti subpopulation in the context of a long-term field release experiment with genetically modified S. melilati strains. The presence of many insertion sequences has suggested that these elements mediated acquisition of accessory plasmid modules.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 2006
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Role of the ssu and seu genes of corynebacterium glutamicum ATCC 13032 in utilization of sulfonates and sulfonate esters as sulfur sources
Article Abstract:
Corynebacterium glutamicum ATCC 13032 was found to be able to utilize a broad range of sulfonates and sulfonate esters as sulfur sources. By using real-time reverse transcription-PCR, the ssu and seu gene cluster was found to be expressed considerably more strongly during growth of sulfonates and sulfonate esters than during growth on sulfate.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 2005
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