Long-term production of ergot peptides by immobilized Claviceps purpurea in semicontinuous and continuous culture
Article Abstract:
Continuous and semicontinuous cultures of Claviceps purpurea 1029/N5 were achieved by immobilization on calcium alginate beads. Mycelial immobilization resulted in prolongation of growth and production of ergotamine. Optimal ergotamine production occured by increasing calcium chloride concentration, which prolonged the productive phase. In addition, restricting the phosphate supply inhibited the production of outgrowing hyphae.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 1993
User Contributions:
Comment about this article or add new information about this topic:
Comparison of ergot alkaloid biosynthesis gene clusters in Claviceps species indicates loss of late pathway steps in evolution of C. fusiformis
Article Abstract:
The Claviceps fusiforms ergot alkaloids synthesis (EAS) is analyzed in order to examine the evolutionary basis for chemotypic differences between the Claviceps species. The studies have shown that the Claviceps fusiformis EAS cluster has evolved from a more complete cluster by loss of some lps gene and by rearrangements and mutations inactivating lpsB and cloA.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 2007
User Contributions:
Comment about this article or add new information about this topic:
Chemoraces and habitat specialization of Claviceps purpurea populations
Article Abstract:
Researchers identified three groups of Claviceps purpurea that occupied different habitats. One was found in fields and open meadows, one in shady or wet habitats, and one in salt marshes. Techniques included randomly amplified polymorphic DNA, EcoRI restriction site polymorphisms in 5.8S ribosomal DNA, alkaloids, and conidial morphology.
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 2000
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Regulation of myogenesis in paralyzed muscles in the mouse mutants peroneal muscular dysgenesis. Formation of myotubes in aneural rat muscles
- Abstracts: Overproduction of lignin peroxidase by Phanerochaete chrysosporium (BKM-F-1767) under nonlimiting nutrient conditions
- Abstracts: Investigation of the effect of combined variations in temperature, pH, and NaCl concentration on nisin inhibition of Listeria monocytogenes and Staphylococcus aureus
- Abstracts: An SH3-SH2-SH3 protein is required for p21(Ras 1) activation and binds to sevenless and Sos proteins in vitro
- Abstracts: Transduction, restriction and recombination patterns in Escherichia coli. Sequence comparisons