MiRP2 forms potassium channels in skeletal muscle with Kv3.4 and is associated with periodic paralysis

Article Abstract:

Research has been conducted on the voltage-gated potassium channel of skeletal muscle. Results indicate that it contains MinK-related peptide 2 and pore-forming subunit Kv3.4 and that MinK-related peptide 2 operates with a potassium channel subunit in governing skeletal muscle function and pathophysiology.

United States, Peptides, Striated muscle, Potassium channels, Physiology, Pathological, Pathological physiology, Paralysis

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Amyotropic lateral sclerosis: unfolding the toxicity of the misfolded

Article Abstract:

The review of the publications on the amyotropic lateral sclerosis, an adult-onset disease is presented. The points of interest include genes and risk factors for the amyotropic lateral sclerosis, toxicity of superoxide dismutase 1 mutants, apoptotic death and mitochondrial defects.

Canada, Gene mutations, Gene mutation, Genetic aspects, Cell death, Mitochondria, Toxins, Amyotrophic lateral sclerosis

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