Mycolic acid composition of Corynebacterium glutamicum and its cell surface mutants: effects of growth with glycine and isonicotinic acid hydrazide

Article Abstract:

An analysis on the fatty acid and mycolic acid composition of Corynebacterium glutamicum strain ATCC 13059 and other selected mutants belonging to the corynebacteria species was conducted. C. glutamicum and other sources were primarily subjected to strains, media and growth conditions. Findings of the research include the analysis that the specific growth rates of all strains tested decreased as the concentration of glycine or INH in growth medium increased. Furthermore, the models for synthesis of mycolic acid suggested that cellular fatty acids undergo chain elongation and modification.

Cell membranes, Fatty acids, Plasma membranes, Fatty acid synthesis, Organic acids

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Context-sensitive transposition of IS6110 in mycobacteria

Article Abstract:

Research was conducted to examine whether expression of the chromosomal insertion elements is influenced by the activity of the site of transposition. The data indicate that the effect of transposition is dependent on the orientation of the transposed elements with respect to flanking sequences in the plasmid.

Usage, Observations, Plasmids, Translocation (Genetics), Epidemiology, Insertion elements, DNA, DNA insertion elements, Tuberculosis vaccines

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Separation and characterization of individual mycolic acids in representative mycobacteria

Article Abstract:

Characterization and separation of individual mycolic acids has been undertaken in 24 representative mycobacteria. The stereochemistry of the double bonds and cyclopropane rings and the chain lengths of each of the separated component mycolates was assayed.

Japan, Sweden, Statistical Data Included, Reports, Physiological aspects, Tuberculosis, Mycobacterium tuberculosis, Mycobacteria, Mycobacterium, Chemical bonds, Stereochemistry

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