Orchestral maneuvers in the axon: trio and the control of axon guidance

Article Abstract:

Orchestral actions in the axon involving trio and the control of axon guidance are discussed in this minireview article. The ways in which a group of independent genetic studies comes together on the very versatile growth cone molecule, a dynamic and mobile structure at the axon's distal end, are the focus.

Research, Cellular signal transduction, Cytochemistry, Axons

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EphB receptors interact with NMDA receptors and regulate excitatory synapse formation

Article Abstract:

Research demonstrates that EphrinB activation leads to the recruitment of N-methyl-D-aspartate receptors to EphB receptor complexes, which influences the synapse development and/or function. Data indicate that unusually the extracellular domains of the EphB and the receptors mediate their interaction.

Protein tyrosine kinase, Protein-tyrosine kinase, Neural transmission, Synapses, Neurotransmitter receptors, Neural transmission regulation

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Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms

Article Abstract:

Research has been conducted on the bHLH transcription factor neurogenin (Ngn1) inhibiting neural stem cell differentiation into astrocytes. Results indicate that Ngn1 effectively inhibits astrocyte differentiation, and the Ngn1 glial-specific gene-transcription repression mechanisms have been identified.

Spain, Statistical Data Included, Analysis, Genetic transcription, Transcription (Genetics), Stem cells, Developmental neurology, Cell research, Cytological research, Astrocytes

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