Nitric oxide contributes to behavioral, cellular, and developmental responses to low oxygen in Drosophila
Article Abstract:
Drosophila embryos were used to investigate the effects of hypoxia and nitric oxide signalling pathway on larval behavior and cell cycle. Studies have confirmed that Drosophila embryos and larvae can survive extended periods of hypoxia. Drosophila larvae also exhibit rapid and reversible responses to hypoxia which include developmental arrest, cell cycle blocks and larval behavioral changes. Findings have indicated that nitric oxide and protein kinase G contribute to the Drosophila's ability to respond to oxygen deprivation.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1999
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The eye-specification proteins so and eya form a complex and regulate multiple steps in Drosophila eye development
Article Abstract:
Sine oculus (so) and eyes absent (eya) are needed for Drosophila eye development, and are members of the mammalian Six and Eya gene families. The genes are thought to act with eyeless (Pa6) in regulating eye development in vertebrates and invertebrates. It is demonstrated the So and Eya regulate steps in eye development such as cell proliferation, neuronal development and patterning.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1997
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