Operon prediction for sequenced bacterial genomes without experimental information

Article Abstract:

A Bayesian hidden Markov model that incorporates comparative genomic data with traditional predictors such as intergenic distances was constructed to explore the possibility of using phylogenetic information to aid in operon prediction. The findings show that the constructed algorithm is capable of highly sensitive and accurate operon prediction in a wide range of bacterial genomes and that these predictions could lead to the rapid discovery of new functional relationships among genes.

Phylogeny, Markov processes

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Diversity of telomere palindromic sequences and replication genes among 'Streptomyces' linear plasmids

Article Abstract:

A population of 'Streptomyces' strains was investigated. The results of the study indicated an unexpected diversity of telomere palindromic sequences and replication genes among 'Streptomyces' linear plasmids.

Genetic aspects, Telomeres, Streptomyces

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