Process of protein transport by the type III secretion system

Article Abstract:

One of the most widespread ways for translocating bacterial proteins into host cells is through the type III secretion system (TTSS). The TTSS apparatus is composed of approximately 20 to 25 different proteins and most of the conserved TTSS proteins are similar in sequence to proteins that make up parts of the basal body of the bacterial flagellum.

Flagella (Microbiology), Flagella, Bacterial proteins

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Metagenomics: Application of genomics to uncultured microorganisms

Article Abstract:

Metagenomics can provide the tools to balance the abundance of knowledge attained from culturing with an understanding of the uncultured majority of microbial life. Metagenomics has changed the way microbiologists approach many problems, redefined the concept of a genome, and accelerated the rate of gene discovery.

Microbial genetics, Genomics

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Rabbit and nonhuman primate models of toxin-targeting human anthrax vaccines

Article Abstract:

AVA- and rPA-based anthrax vaccines provide high-level and lasting protection against aerosol challenge with a diverse panel of B. anthracis isolates in rhesus macaques. AVA also protects rabbits against aerosol challenge with multiple B. anthracis isolates in a vaccine dose-dependent manner.

Influence, Rabbits, Anthrax vaccine, Anthrax vaccines

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