Prokaryotic and eukaryotic replicons
Article Abstract:
In a conference to discuss the models of Prokaryotic and Eukaryotic Replicons, scientists from around the world provided evidence for the vitality of the replicon model and also highlighted the developments relating to a wide variety of replicons. The replicon model which was proposed by Jacob and Brenner in 1963 to explain the regulation of prokaryotic DNA replication, has proved very vital. The replicon model with minute modification may be used to understand the process of regulation of DNA replication in all organisms.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1995
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A gene essential for de novo methylation and development in Ascobolus reveals a novel type of eukaryotic DNA methyltransferase structure
Article Abstract:
Research was conducted to examine the characterization and cloning of an Ascobolus gene, masc1, encoding a protein with the primary structure of a DNA methyltransferase (MTase). The disruption of masc1 has no effect on viability or maintenance methylation but prevents the de novo methylation associated with methylation induced premeiotically process. Thus, Masc1, the gene product which is involved in de novo methylation, is likely to represent a novel type of a eukaryotic MTase.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1997
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Many paths to the top of the mountain: diverse evolutionary solutions to centromere structure
Article Abstract:
Diverse evolutionary solutions to centromere structure are discussed in this minireview article which focuses on the emerging molecular view of the diversity and the ways in which it contributes to the view of the function of centromeres. Topics include Arabidopsis centromeres, centromeric protein conservation and variation, and reasons for the diversity. Centromeres are required for accurate transmission of chromosomes in eukaryotes.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2000
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