Vanadium interferes with siderophore-mediated iron uptake in Pseudomonas aeruginosa

Article Abstract:

Vanadium has been found to interfere with siderophore-mediated iron uptake in Pseudomonas aeruginosa. V-pyochelin (PCH) catalyses a Fenton-type reaction in which the toxic superoxide anion O(sub.2)(super.-) is generated. PCH-negative mutants were seen to be more resistant to vanadium than the wild-type strain.

Germany, Belgium, Bacteria, Vanadium

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Pseudomonas aeruginosa mediated apoptosis requires the ATP-ribosylating activity of ExoS

Article Abstract:

Pseudomonas aeruginosa-mediated apoptosis has been found to require ATP-ribosylating activity of ExoS. The organism is an opportunistic one that infects the immunocompromised and those with cystic fibrosis for the most part. Invasive strains of P. aeruginosa have been found, using a tissue culture system, to induce apoptosis at high frequency in HeLa and other epithelial and fibroblast cell lines. Mutants in P. aeruginosa exo5 do not induce apoptosis, and complementation with wild-type exoS restored apoptosis-inducing ability. .

Cell death, Bacteria, Pathogenic, Pathogenic bacteria, Variation (Biology), Adenosine diphosphate, Ribose

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Siderophore uptake and use by the yeast Saccharomyces cerevisiae

Article Abstract:

Saccharomyces cerevisiae siderophore uptake and use has been studied with attention to specificity, energy requirements, regulation and intracellular iron use. The nonreductive uptake of ferrichrome, ferrioxamine B, ferricrocin, and triacetylfusarinine C.

Yeast, Saccharomyces, Yeast (Food product), Cells, Cell permeability, Oxidation-reduction reaction, Oxidation-reduction reactions

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