Dedifferentiation of mammalian myotubes induced by msx1

Article Abstract:

Results demonstrate that in the cell differentiation process, terminally differentiated mice myotubes can dedifferentiate through msx1 gene expression. Data indicate that clonal populations of the induced mononucleated cells redifferentiate into skeletal muscle cells upon receiving proper signals from the msx1 gene.

Striated muscle, Cell differentiation, Mammals, Myogenesis

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Molecular and cellular mechanisms of cardiac arrhythmias

Article Abstract:

The review of the publications on the mechanical activity of the heart is presented. The points of interest include cardiac arrhythmias and sudden death, a familial cardiac arrhythmia and mutations in cardiac ion channel genes.

Statistical Data Included, Analysis, Causes of, Gene mutations, Gene mutation, Sudden death, Ion channels, Arrhythmia, Cell research, Cytological research, Cardia

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LIM-kinase1 hemizygosity implicated in impaired visuospatial constructive cognition

Article Abstract:

The developmental disorder Williams syndrome (WS) was studied to identify which genes are essential to human cognitive development. Two families with a partial WS phenotype were described, with affected family members having the specific WS cognitive profile but lacking other WS characteristics. Results show that the hemizygosity of the LIM-kinase1 protein kinase gene will likely result in impaired visuospatial constructive cognition in WS.

Cognition, Developmental disabilities, Heredity

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