A novel family of mammalian taste receptors

Article Abstract:

Researchers report the discovery of 40 to 80 taste receptors that respond to bitter tastes. The T2R receptors occur only in taste receptor cells that have the G protein alpha subunit gustducin.

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T2Rs function as bitter taste receptors

Article Abstract:

Researchers report the discovery of the taste receptor that responds to bitter tastes. It is associated with the G protein alpha subunit gustducin, which mediates bitter tastes.

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Putative mammalian taste receptors: a class of taste-specific GPCRs with distinct topographic selectivity

Article Abstract:

Taste perception in mammals starts with the recognition of tastant molecules by unidentified membrane receptors localized on the apical surface of receptor cells of the tongue and palate epithelium. Two novel seven-transmembrane domain proteins expressed in topographically distinct subpopulations of taste receptor cells and taste buds were cloned and characterized. These proteins are specifically found in the taste pore and are members of a new group of G-protein coupled receptors.

Physiological aspects, Proteins, Cell receptors, G proteins, Tongue, Palate

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