RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides
Article Abstract:
A study was conducted to determine how S100/calgranulin polypeptides control the inflammatory process of cells. Results indiacte that two members of the S100/calgranulin polypeptide family, namely, receptor for advanced glycation end (RAGE) and the extracellular newly identified RAGE-binding proteins, facilitate the activation of endothelial cells, macrophages and lymphocytes that trigger the inflammatory process.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1999
User Contributions:
Comment about this article or add new information about this topic:
A new map for navigating the yeast epigenome
Article Abstract:
The epigenetic map is a new and reliable genome-wide microarray study of histone modifications and gene expression in yeast. The epigenetic map is widely used in the research of epigenome.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2005
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Analysis of mitochondrial DNA indicates that domestic sheep are derived from two different ancestral maternal sources: No evidence for contributions from Urial and Argali sheep
- Abstracts: JUN cooperates with the ETS domain protein pointed to induce photoreceptor R7 fate in the Drosophila eye. A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span
- Abstracts: [alpha]3Na[.sup.+]/K[.sup.+]-ATPase is a neuronal receptor for agrin. Snaring the function of alpha-synuclein
- Abstracts: Fibrinogen, homocyst(e)ine, and C-reactive protein concentrations relative to sex and socioeconomic status in British young people
- Abstracts: Yeast TAF(sub II)145 functions as a core promoter selectivity factor, not a general coactivator