Recent advances in IL-6 related to autoimmunity
Article Abstract:
Interleukin-6 (IL-6), a multifunctional cytokine that induces differentiation of B cells to antibody-producing plasma cells has promoted the development of T-helper 17 cells that affect the pathogenesis of autoimmune diseases. The analysis of IL-6 has suggested that IL-6 might be a vital factor to polarize, to increase T helper cells (Th17) and to inhibit regulatory T cells, leading to autoimmunity.
Publication Name: The Scientist
Subject: Biological sciences
ISSN: 0890-3670
Year: 2007
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The cause: A balanced attack
Article Abstract:
The discovery and characterization of the regulatory pathways might lead to the discovery of new drugs and cell therapies for autoimmune diseases. Scientists studying autoimmunity are trying to understand the homeostasis in the immune system, including balance within and between central and peripheral tolerance.
Publication Name: The Scientist
Subject: Biological sciences
ISSN: 0890-3670
Year: 2007
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A bonanza of B-cell therapies
Article Abstract:
New treatment approaches have provided hope for patients with autoimmune diseases, especially rheumatoid arthritis and lupus. Biologic therapies targeting B-cells are found to be extremely effective and safe and scientists are researching on the role played by B-cells in autoimmunity.
Publication Name: The Scientist
Subject: Biological sciences
ISSN: 0890-3670
Year: 2007
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