Connecting cancer to the asymmetric division of stem cells
Article Abstract:
A study demonstration that the cell-fate determinant Brain Tumor (Brat) suppresses self-renewal in one of the daughter cells that arises from the asymmetric division of a neural stem cell is presented. The findings suggest a mechanism by which loss of polarity in stem cells might lead to tumorigenesis.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
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Bacterial mitotic machineries
Article Abstract:
Fundamental new insight into the molecular mechanisms behind plasmid and chromosome segregation in prokaryotic cells is reviewed. A study is conducted to show how prokaryotic actin homologs form mitotic machineries that segregate DNA before cell division.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2004
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Coordination of cell division and chromosome segregation by a nucleoid occlusion protein in Bacillus subtilis
Article Abstract:
The identification of a specific effector of nucleoid occlusion in Bacillus subtilis is discussed. YyaA contributes to the correct placement of the division site and reduces the risk of chromosome damage during division.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2004
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