Synapse signalling complexes and networks: machines underlying cognition

Article Abstract:

Research findings indicate that synapses contain N-methyl-D-aspartate receptor complexes, which function as molecular machines processing informaion encoded in neural activity paterns. Data show that the multicomponent synapses are capable of activation by calcium influx from ion channels and receptors. Furthermore, the protein network of the synapses are involved in neuronal plasticity and cognition.

United Kingdom, Physiological aspects, Composition, Cognition, Neuroplasticity, Synapses

---

Motor protein control of ion flux is an early step in embryonic left-right asymmetry

Article Abstract:

The invariant left-right asymmetry of animal body plans raises fascinating questions in cell, developmental, evolutionary, and neuro-biology. Based on wide-ranging data on ion fluxes and motor protein action in a number of species, a model is proposed whereby laterality is generated much earlier, by asymmetric transport of ions, which results in pH/voltage gradients across the midline.

Proteins, Ions, Animal genetics, Genetic research, Embryo

---

CREB, neurogenesis and depression

Article Abstract:

The induction of the transcription factor, cAMP response element-binding protein (CREB) in the signaling pathways for pathogenesis and a therapy of depression is studied. The use of CREB in wild-type mice shows that it helps in regulating neurogenesis, which then helps in reducing depression in any living being.

Depression, Mental, Depression (Mood disorder), Genetic aspects, Cyclic adenosine monophosphate response element-binding protein

Similar abstracts:

• Abstracts: Conjugative plasmid transfer between bacteria under simulated marine oligotrophic conditions. Plasmid transfer between narine bacteria in the aqueous phase and biofilms in reactor microcosms
• Abstracts: Synaptic transmission: a bidirectional and self-modifiable form of cell-cell communication. Synaptic structure and function: dynamic organization yields architectural precision
• Abstracts: Wnt/[beta]-catenin signaling regulates vertebrate limb regeneration. Under arrest: cytostatic factor (CSF)-mediated metaphase arrest in vertebrate eggs
• Abstracts: Expression of fragile sites triggers intrachromosomal mammalian gene amplification and sets boundaries to early amplicons
• Abstracts: Perpetuating the double helix: molecular machines at eukaryotic DNA replication origins. Chromatin remodeling by ATP-dependent molecular machines

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.