Telomere length homeostatis is achieved via a switch between telomerase-extendible and -nonextendible states
Article Abstract:
A study to measure telomere elongation at nucleotide resolution in Saccharomyces cerevisiae though the cell cycle varies between a few to more than 100 nucleotides and is independent of telomere length is presented. Thus, it is shown that telomere length homeostatis is achieved via a switch between telomerase-extendible and -nonextendible states by taking a molecular snapshot of a single round of telomere replication.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2004
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Telomerase repeat addition processivity is increased at critically short telomeres in a Tel1-dependent manner in Saccharomyces cerevisiae
Article Abstract:
A complete analysis of telomerase, a ribonucleoprotein enzyme that elongates telomeres to counteract telomere shortening is presented. Results prove that the telomerase repeat addition processivity is increased at critically short telomeres in a Tel1-dependent manner in Saccharomyces cerevisiae.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2007
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A class of membrane proteins shaping the tubular endoplasmic reticulum
Article Abstract:
The identification of membrane proteins involved in endoplasmic reticulum (ER) network formation is discussed. The major components shaping the tubular ER are the reticulons and the interacting protein DP1/Yop 1p.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
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