The Drosophila couch potato gene: an essential gene required for normal adult behavior
Article Abstract:
A new Drosophila gene, designated couch potato (cpo) was isolated and characterized. The gene is expressed in the sensory mother cells, in the embryonic peripheral nervous system (PNS) and in the glial cells of the PNS and the central nervous system. Mutations in cpo resulted in embryo inviability and abnormal adult behavior. However, adult cpo mutants did not have any obvious morphological defects. Its expression pattern suggests that itmay play an important role in the PNS or in the glia.
Publication Name: Genetics
Subject: Biological sciences
ISSN: 0016-6731
Year: 1992
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Dacapo, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosophila development
Article Abstract:
The role of dacapo (dap) gene during programmed embryonic cell differentiation was analyzed during epidermal cell differentiation in Drosophila embryos. The Drosophila dap gene regulates epidermal cell differentiation by encoding a cyclin-dependent kinase inhibitor protein which arrests cell proliferation in the embryonic epidermis. Furthermore, the DAP protein binds with cyclin E/cdk2 complexes during embryogenesis to intiate G1 arrest in epidermal cells.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1996
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P-element mutations affecting embryonic peripheral nervous system development in Drosophila melanogaster
Article Abstract:
The molecular processes which control the neural development in Drosophila melanogaster is investigated using the Drosophila embryonic peripheral nervous system (PNS). About 2000 lethal p-element insertion strains are screened by identifying the PNS development controlling genes. A neural specific marker MAb 22C10 and 92 mutant strains are used for the examination of the PNS of the mutant embryos.
Publication Name: Genetics
Subject: Biological sciences
ISSN: 0016-6731
Year: 1995
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- Abstracts: The product of the yvoC (gerF) gene of Bacillus subtilis is required for spore germination. Transcriptional responses during outgrowth of Bacillus subtilis endospores
- Abstracts: The Drosophila SDE3 homolog armitage is required for oskar mRNA silencing and embryonic axis specification. In vivo analysis of Drosophila bicoid mRNA localization reveals a novel microtubule-dependent axis specification pathway
- Abstracts: The Drosophila clock gene double-time encodes a protein closely related to human casein kinase I epsilon. Double-time is a novel Drosophila clock gene that regulates period protein accumulation
- Abstracts: The heterochromatin-associated protein HP-1 is an essential protein in Drosophila with dosage-dependent effects on position-effect variegation