The Suppressor of fused gene encodes a novel PEST protein involved in Drosophila segment polarity establishment
Article Abstract:
Segmentation polarity genes in Drosophila melanogaster are activated by pair rule gene activity. Suppressor of fused (Su(fu)) is a dominant suppressor of the fused gene that has been designated as a tool of analysis for regulatory pathways in gene activity. The Su(fu) protein is characterized by a PEST sequence and exhibited no substantial homologies with known proteins. Ideal segment formation is conditioned by appropriate genetic doses of fu and Su(fu).
Publication Name: Genetics
Subject: Biological sciences
ISSN: 0016-6731
Year: 1995
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Modulation of the Suppressor of fused protein regulates the Hedgehog signaling pathway in Drosophila embryo and imaginal discs
Article Abstract:
The role of Suppressor of fused protein, which is antagonized by the Fused protein, as a negative regulator of Hedgehog target gene expression in embryonic development of Drosophila is examined.
Publication Name: Developmental Biology
Subject: Biological sciences
ISSN: 0012-1606
Year: 2006
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Atrophin contributes to the negative regulation of epidermal growth factor receptor signaling in Drosophila
Article Abstract:
The negative impact of atrophin in controlling epidermal growth factor receptor (EGFR) signaling in Drosophila is studied.
Publication Name: Developmental Biology
Subject: Biological sciences
ISSN: 0012-1606
Year: 2006
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